Cutaneous mucinosis is a medical term used for a diverse group of skin disorders which involve a localized or widespread accumulation of mucin or glycosaminoglycan (GAG) in the skin or within the hair follicle.
The disorders grouped under cutaneous mucinosis occur because of the production of usually large amounts of mucin by fibroblasts. Mucin is a jelly-like complex carbohydrate substance – mucopolysaccharides acid or, more commonly, hyaluronic acid – which normally occurs as part of the connective tissue in the dermis or middle layer of the skin. The main function of mucin is to maintain the balance of salt and water within the dermis.
Cutaneous mucinosis is generally not reported in association with mixed connective tissue disease (MCTD). However, the condition can sometimes occur in certain diffuse connective tissue diseases (DCTD) like Lupus erythematosus, Rheumatoid arthritis, Dermatomyositis, Vasculitis, Sjogren’s syndrome, and Systemic sclerosis.
In people affected by cutaneous mucinosis, abnormal amounts of mucin get deposited in the skin and its annexes (the interstices of the dermis). The excessive deposition of mucin manifests as a clinically specific lesion or a mucinous rash. The clinical cutaneous manifestation of mucin is generally described either as dermal or epidermal (follicular).
Cutaneous Mucinosis: Types
Cutaneous mucinosis can be classified into two groups:
(i)Primary cutaneous mucinoses: This group of disorders is associated with a metabolic process. The disorders manifest with clinical dermatologic applications, and include conditions like lichen myxedema, reticular erythematous mucinosis and scleromyxedema.
(ii) Secondary cutaneous mucinoses: In this group, the occurrence of cutaneous mucinosis is a result of a catabolic process. This group of disorders is linked to other diseases,including thyroid diseases, toxic diseases (toxic oil syndrome), DCTD, nephrogenic fibrosing dermopathy, Eosinophilia-Myalgia Syndrome, and cancer.
Cutaneous Mucinosis: Causes
The underlying cause of cutaneous mucinosis is not known. Nonetheless, in some cases, the mucinosis appears to be linked to circulating antibodies that stimulate the synthesis of GAGs by skin fibroblasts.
Although the release of cytokines is an important factor which regulates the production of mucin, doctors still not know the exact cause behind the abnormal mucin production which causes Cutaneous mucinosis group of skin disorders.
Cutaneous Mucinosis: Symptoms
The most prominent symptom of cutaneous mucinosis is the appearance of a violaceous, scaly, and erythematous rash on the skin, either diffusely or locally at a specific site.
The manifestations of the cutaneous mucinosis rash can be quite diverse. It can be described differently as follows:
- Plaque-like rash
- Papular rash
- Heliotrope rash
- Diffuse mucinous rash that may involve the face, chest, back, and all extremities.
Overall, in people suffering from cutaneous mucinosis, the excess mucin accumulation in the dermis gives a waxy appearance to the skin, and leads to the formation of plaques, papules, and nodules.
Cutaneous Mucinosis: Treatment
The treatment of cutaneous mucinosis depends on the reason which triggers the skin disorder. However, in general terms, the treatment includes the use of specific drugs, injections, immunosuppressant agents, and other therapies which can facilitate the regression of the disorder before it becomes serious.
Cutaneous mucinosis can also be effectively managed with the help of Ayurvedic products. Planet Ayurveda herbal manufacturing company offers some excellent herbal formulations for skincare which can be beneficial for managing various types of skin disorders including cutaneous mucinosis.
1. Neem Capsules
Standardized and pure extract of ‘Neem’ herb (Azadirachta Indica) is used for preparing these capsules. The potent herb is widely known for its antiviral, antioxidant, antibacterial, anti fungal, and blood-purification properties.
The use of Neem capsules can benefit people affected by Cutaneous mucinosis because the capsules can boost the immune system, purify blood, and manage a number of skin disorders, including dermatitis, skin rashes, warts, acne, eczema, psoriasis, cold sores, boils, and Scabies.
Dosage– 1 capsule two times a day with plain water after meals.
2. Radiant Skin Hair Nails Formula
This product – in capsule form – is an excellent herbal formulation for special care of skin, hair and nails. These capsules are prepared from a combination of herbs including Manjistha (Rubia cordifolia), Chirata (Swertia chirayita), Pit papda (Fumaria officinalis), and Grit kumari (Aloe barbadensis).
Patients suffering from Cutaneous mucinosis can benefit from the use of these capsules because the herbal ingredients can support healthy skin and body, make the skin firm and smooth, and treat several skin conditions like acne, pimples, ringworm, and psoriasis.
Dosage-1 capsule two times a day with plain water after meals.
3. Gandhak Rasayan Tablets
The preparation of these tablets involves the use of pure Gandhak (Sulphur purified) and pure sugar, which are combined with some other beneficial natural ingredients which have anti-inflammatory, antiviral, antibacterial, and antimicrobial properties.
The use of these tablets is beneficial for patients affected by Cutaneous mucinosis because the herbal ingredients can keep the skin healthy, remove the skin’s dead surface, boost the immune system, manage inflammation, treat fungal infections, reduce the outbreak of acne/pimples, and balance the body’s Vata, Pitta and Kapha doshas.
Dosage– 2 tablets two times a day with plain water after meals.
4. Manjistha Capsules
Standardized extract of ‘Manjistha’ herb (Rubia cordifolia) is used for preparing these capsules. The potent herb has anti-inflammatory, anti-bacterial, anti-microbial, astringent, antispasmodic, blood-purifier, and immunity-enhancer properties.
These capsules can benefit people suffering from cutaneous mucinosis because of Manjistha’s ability to treat various skin diseases, improve the complexion, eliminate toxins from the body, manage blood disorders, and pacify the Pitta dosha.
Dosage– 1 capsule two times a day with plain water after meals.
5. Nirgundi Oil
The preparation of this oil involves the use of the multipurpose ‘Nirgundi’ herb (Vitexnegundo). The oil can be applied topically on the skin to treat a number of skin disorders.
The use of Nirgundi oil is beneficial for managing cutaneous mucinosis because of Nirgundi’s antioxidant, anticonvulsant, hepatoprotective actions. The oil has the ability to manage several skin conditions, and reduce inflammation.
Dosage-This is needed to be applied on affected skin with the help of cotton swab, two or three times a day.
6. Tea Tree-Aloe Vera Premium Handmade Bathing Bar
This bathing bar is prepared from a combination of herbal components including Tea tree oil (Melaleuca alternifolia), Aloe Vera extract (Aloe Barbadensis), Coconut oil (Cocos nucifera), Castor oil (Ricinus communis), Cotton seed oil (Gossypium Herbaceum), and Palm oil (Elaeis guineensis).
This bathing bar can benefit the patients suffering from cutaneous mucinosis because it can treat dry and damaged skin, rashes, pimples, skin infections, psoriasis, and eczema. The use of the bathing bar can also reduce oiliness and heal skin inflammation.
How to use it– Gently apply soap over the wet area on facial skin as well as body, then wash with water. This can be used one time or two times as per the requirement.
Planet Ayurveda’s herbal products for managing cutaneous mucinosis are prepared from pure and natural herbs. These products do not contain any chemicals, additives, fillers, binders, artificial colors, or preservatives. However, it is recommended that people suffering from cutaneous mucinosis should use these products in consultation with an Ayurveda practitioner.
Q1: Does cutaneous mucinosis occur in association with mixed connective tissue disease (MCTD)?
Ans: No. Cutaneous mucinosis does not generally occur in association with mixed connective tissue disease.
Q2: What is the possibility of occurrence of cutaneous mucinosis in Lupus erythematosus (LE) cases?
Ans: The occurrence of cutaneous mucinosis is possible in up to 1.5% of LE cases.
Q3: Can the characteristics of the Primary Cutaneous mucinosis and Secondary Cutaneous mucinosis overlap?
Ans: Yes. The characteristics of the Primary Cutaneous mucinosis and Secondary Cutaneous mucinosis can overlap.
Q4: How varied can be the abnormal mucin deposits which occur in cutaneous mucinosis?
Ans: The abnormal mucin deposits which occur in cutaneous mucinosis can be quite varied — ranging from minor cosmetic problems to potentially serious disorders involving internal organs.
Q5: What is Follicular mucinoses?
Ans: Follicular mucinoses is a type of Primary Cutaneous mucinosis in which excess mucin gets deposited in the epithelial hair follicle sheaths and sebaceous glands.
Contact Planet Ayurveda Support Team to provide you the costing/ordering and delivery information at – email@example.com or Call at 0172-521-4030 (India), +91-172-521-4030 (Outside India) or Whatsapp at (+91) 9915-593-604.