Best Alternative to Selegiline for Parkinson’s Disease
Abstract
Parkinson’s disease/ Kampavata is a common neuro-disorder affecting 0.3% of the general population globally and its prevalence rate is higher in men than women. According to medical surveys and the World Health Organization, about 80% of the total population globally rely on herbal treatment due to increased side effects from synthetic drugs, high cost, emerging ailments, etc. Moreover, Ayurveda is a traditional Indian medicinal system and is self-healing science in itself. It is known to be a complete package of ethical, spiritual and psychological health. Ayurveda is considered to have the ability to treat effectively various chronic diseases as it balances Tridosha i.e. Vata, Pitta, and Kapha exceptionally that too naturally. (5)
What is Parkinson’s Disease?
Parkinson’s disease is a progressive and common neurodegenerative chronic disorder that was first described by Dr. James Parkinson as “shaking palsy”. This disease is characterized by motor and non-motor traits which cause degenerative effects on controlling muscles and mobility. The prevalence of the disease is approximately 20 cases per 60,000 per year and mostly affect at 60 years of age. The incidence of the disease is increasing by 1% to 3% in the age group of people above 80 years. (1)
What are the Signs and Symptoms of Parkinson’s Disease?
Some of the various motor and non-motor symptoms are as follows-
- Depression, anxiety, panic attacks, etc.
- Fatigue
- Digestive disorders like constipation
- Tremor
- Problem in balancing
- Sleeping disorders
- Instable postures
- Urinary infections
- Dementia
- Olfactory inability
- Hallucinations and illusions
- Psychosis
- Dyskinesia
- Bradykinesia
- Sialorrhea
- Hyposmia
- Increased muscles rigidity
- Freezing gait (2) (3)
What are the Factors that Trigger the Onset of Parkinson’s Disease?
Some of the factors and conditions that cause the onset of this disease are-
- Elevated cholesterol levels
- Exposure to various environmental toxins like herbicides, pesticides, cyanide, heavy metals, and other solvents.
- Increased calorie intake
- Increased weight or Body mass index
- Impaired mitochondrial
- Triggered toxicity levels
- Smoking habits
- Accelerate aging
- Increased Caffeine intake (1) (2)
How it can be Diagnosed?
Other than the history of patients, physical aspects there are some of the clinical manifestations involved in diagnosis and confirmation of this disease are-
- MRI (Magnetic resonance imaging)
- PET (Positron emission tomography)
- SPECT (Single-photon emission computed tomography) (4)
Treatment
According to the modern medical system, only symptoms in Parkinson’s disease can be managed by medication, not the disease itself. Certain medications that are mostly recommended to reduce the symptoms are Cardiopa-levodopa, dopamine agonists, some MAO-B inhibitors like Selegiline, amantadine, safinamide and rasagiline, some COMT (Catechol O-methyltransferase) inhibitors, etc.
What are Selegiline and its Side Effects?
Selegiline is an MAO-B inhibitor which is considered as an enzyme blocker used for treating movement disorders, tremor, stiffed muscles, etc. It also breaks down certain substances like dopamine and serotonin.
Side Effects
Selegiline (levodopa) may cause dizziness, abdominal pain, nausea, sleep disorders, hallucinations, mood swings, headaches, etc. In this condition you may need to change your mode of medication or stop taking this otherwise side effects may get worse.
The Best Ayurvedic Alternative to Selegiline for Parkinson’s disease
According to Ayurvedic principles, it is clear that herbs manages every ailment naturally without any side effect and works effectively. There are also various herbs for the treatment of Parkinson’s disease that do not produce any side effects like selegiline. Planet Ayurveda offers the best herbal alternative to selegiline for Parkinson’s disease. Planet Ayurveda is offering 100 % pure and natural herbal remedies for treating Parkinson’s disease. Parkinson’s care pack treats this disease effectively and the product description is given below. All the products formulated are manufactured under the strict supervision of MD Ayurveda’s and are free from any kind of chemicals, preservatives, additives, fillers, colors, starch, etc. Products are prepared from high-quality herbs and don’t have any side effects.
Product Description
1. Ashwagandha Capsules
Ashwagandha capsules have been prepared from root extracts of high-quality herbs of Ashwagandha (Withania somnifera). This is an amazing rejuvenating agent and a great liver & kidney tonic. This herb works efficiently in reducing symptoms of various disorders like anxiety, stress, depression, muscle fatigue, joint pain, arthritis, blood pressure, insomnia, diabetes, etc. Ashwagandha is packed with anti-inflammatory and anti-oxidant agents which makes it beneficial in calming down the stress relieves exhaustion and reduces depression. This product is a great Rasayan and works significantly in pacifying Kapha dosha.
Dosage– 1-2 capsules two times a day with plain water after meals.
2. Brahmi Chyawanprash
Ayurveda has formulated this herbal supplement with enormous medicinally important herbs which are enriched with essential minerals and vitamins. Some of the herbs in the composition are Brahmi (Bacopa monnieri), Dashmoola, Bala (Sida cordifolia), Ashwagandha (Withania somnifera), Bhumi Amla (Phyllanthus niruri), Shatavari (Asparagus racemosus), Jivanti (Leptadenia diffusa), Jeerak (Cuminum cyminum), Kesar (Crocus sativus), etc. This product plays an important role in reducing anxiety, depression, nausea and improves memory problems, anxiety, depression, nausea and improves memory problems. The combination of herbs makes it a great dietary supplement supporting a healthy body and mind.
Dosage– 2-3 full teaspoon twice or thrice a day after meals and give better results with milk.
3. Brahmi Rasayana
Rasayana of Planet Ayurveda has been prepared by the high quality of Brahmi (Bacopa monnieri). Brahmi possesses various therapeutic properties which makes it a great detoxifying agent and brain tonic. This product promotes the regeneration of brain cells which makes it beneficial in reducing symptoms of Parkinson’s disease. It is also beneficial in boosting up the immune system which helps the body to fight against various severe infections. Brahmi contains Bacposide A and B that makes it a great neurological tonic and improves neurotransmission. This product works tremendously in pacifying Vata and Pitta dosha and keeping them in balance.
Dosage– 1-2 capsules two times a day with plain water after meals.
4. Zandopa Powder
Zandopa powder is an amazing herbal formulation that contains seed powder of Mucuna pruriens or velvet bean (Fabaceae). Zandopa is a natural agent of dopamine which is a neurotransmitter that controls the movements of the body. This product works appreciably in improving secondary motor symptoms like facial expressions, speech, posture, etc. associated with Parkinson’s disease. This herbal blend works exceptionally in triggering dopamine levels thus improving all over mental health.
Dosage– 1 teaspoon two times a day with plain water.
References
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517533/
- https://www.ncbi.nlm.nih.gov/books/NBK536722/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367535/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5088077/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041382/
