Adrenoleukodystrophy & Its Ayurvedic Treatment With Herbal Remedies

Abstract

Adrenoleukodystrophy is a genetic condition that damages the myelin sheath that helps to insulate the nerve cells in the brain, it is said to be directly connected to the X-linked chromosome. It affects the nervous system and adrenal glands. Adrenal glands lie on the top of each kidney, also called suprarenal glands, these help to regulate your metabolism, blood pressure, stress, and other essential body functions. Adrenal glands release certain hormones directly into the bloodstream like cortisol, aldosterone, androgenic steroids (oestrogen and androgens), adrenaline, and noradrenaline. These hormones are essential to deal with physical and mental stress, and they all have their own distinct and separate functions. In this particular condition, our body can’t break down the long-chain fatty acids that lead to the accumulation of these chains in the adrenal glands, or the nervous system. In this paper, we are going to discuss the causes, symptoms, epidemiology, and Ayurvedic treatment for Adrenoleukodystrophy.

Adrenoleukodystrophy

Introduction

Adrenoleukodystrophy is a disease linked to X-chromosomes, so it is said to be a genetic disorder that affects the nervous system and adrenal glands. In this condition, myelin sheath starts to deteriorate and helps to insulate the nervous system in the brain and spinal cord. Demyelination occurs in this particular condition, it also leads to damage to the outer layer of the adrenal glands, particularly its cortex part, and results in a deficiency of various hormones. This disease may cause weight loss, weakness, nausea, vomiting, and may end up in a coma. In 1993, ALD-causing genes were identified, it occurs in about 1 in 20,000 to 50,000 people and males are more prone to get affected, females are mostly asymptomatic or may show very few symptoms.

What Is Adrenoleukodystrophy?

Adrenoleukodystrophy affects the nervous system and the adrenal glands and is one of a group of genetic disorders called leukodystrophies that damages the myelin sheath so that it hampers the nerve signals that communicate with the body parts. ALD prevents the body from breaking the very long-chain fatty acids that start to accumulate in the brain, supra-renal glands, and nervous system.

The three major categories of ALD are –

  1. Childhood cerebral ALD
  2. Adrenomyelopathy
  3. Addison’s disease

1. Childhood Cerebral ALD

This condition occurs between the two to ten years of age, and progresses very rapidly, leading to dangerous symptoms like a disabled body and the patient may land into a coma or even result in death. 45% of people are affected by this and shows symptoms like –

  • Attention deficit disorder
  • Dysfunction in vision, hearing, and motor control systems
  • Behavioural problems
  • Dizziness
  • Low blood sugar levels
  • Migraine pain
  • Pain in my eyes

2. Adrenomyelopathy

This condition occurs in adult males, it is much milder than childhood cerebral ALD condition and even it progresses slowly and gradually and does not land into a coma or death. This usually occurs in the 20s or 30s.

  • Walking difficulties
  • Imbalance
  • Gait changes
  • Weakness in arms, legs or spasticity
  • Incontinence
  • Urgency
  • Erectile dysfunction

3. Addison’s Disease

It is a condition that is widely known as adrenal insufficiency. And this is due to the demyelination process or cortex and medulla of adrenal glands that results in insufficient hormonal production from suprarenal glands.

  • Low blood pressure
  • Dark colored skin
  • Nauseatic sensation
  • Stomach pain
  • Fatigue
  • Headache
  • Joint pains

Why are Males more prone to get ALD?

This is an X-linked genetic disorder, it results from a mutated gene on the X-chromosome, females are having two x chromosomes so they can become carriers for this condition, mutated chromosomes will stop working, and non-mutated would take place all the functions of the body. Females usually feel milder symptoms or very less symptoms due to mutated genes. Males have XY chromosome, only one X chromosome, if a mutation occurs on this X chromosome it will affect its normal functioning and cause ALD undoubtedly.

Diagnosis For Adrenoleukodystrophy

  • Newborn screening can show the mutation on a genetic level.
  • Noticeable symptoms can help to make a diagnosis for this disease.
  • If a child has attention deficit disorder or any other neurological disorder, then check for this ALD.

Treatment For Adrenoleukodystrophy

ALD is not a curable disease according to the allopathic medications, they recommend having steroids for adrenal hormonal therapy or cell transplantation, or may prescribe medications for seizures, or muscle stiffness.

Ayurvedic Management For Adrenoleukodystrophy

As we know, allopathic science is still not completely developed and can’t give effective management for genetic disorders. Genetic disorders are directly correlated with beej pradosha vikaras and all of these can be easily managed by Ayurveda procedures, ayurvedic management is properly filled with miraculous herbs that can effectively result in genetic disorders also. Vata, pitta, and Kapha dosha are responsible for all the diseases that develop in our bodies. With the help of some ayurvedic remedies, you can get totally disease-free without getting any side effects.

Herbal Remedies by Planet Ayurveda for Adrenoleukodystrophy

Planet Ayurveda is a GMP-certified herbal manufacturing company that helps patients to cure their diseases in a very natural method. Here, we produce medicines that are totally free from colours, dyes, yeasts, fillers or various chemicals that may harm the patient’s condition and develop side effects on the body. In Planet Ayurveda, the medicines that are prepared are all under the guidance of MD Ayurveda doctors. They make their proper efforts to give 100% natural products without adding any substitutes or adulterants.

  1. Brahmi Capsules
  2. Ashwagandha Capsules
  3. Gotu Kola Capsules
  4. Rasraj Ras
  5. Giloy Capsules
  6. Spirulina Capsules


Ayurvedic Treatment For Adrenoleukodystrophy

Products Description

1. Brahmi Capsules

This is a natural herbal remedy single herbal capsule consisting of Brahmi (Bacopa monnieri) prepared by Planet Ayurveda. Brahmi is used for Vata dosha anuloma, and is used to maintain nerve health and helps to slow down the deterioration process, maintain the balance of the body and act on genetics to reduce its effects on the body. This also helps to reduce the weakness as well as works on attention deficit disorders.

Dosage: 1 Capsule twice daily, with plain water, after meals.

2. Ashwagandha Capsules

This is a patent herbal formulation prepared by planet Ayurveda consisting of Ashwagandha (Withania somnifera). This is a wonderful herb that is very famous for maintaining the nervous system in an adequate manner and nourishing the skeletal system. Ashwagandha is said to be a natural steroidal herb that helps to stimulate the glands to work efficiently. It can show its good effects on adrenocortical insufficiency, or other psychiatric disorders and in loss of intellectual functions.

Dosage: 1 Capsule twice daily, with plain water, after meals.

3. Gotu Kola Capsules

This is a patent herbal formulation prepared by Planet Ayurveda consisting of Gotukola, famous as mandukaparni (Centella asiatica). This is a miraculous herb that works on the blood system and helps to breakdown the very long chains of fatty acids that accumulate in the brain and develop various types of symptoms like imbalance in the body, changes in gait, behavioural problems, dizziness, weakness, nausea, vomiting, these all can develop due to vitiation of vata dosha and mandukaparni is used to balance the Vata dosha effectively.

Dosage: 1 Capsule twice daily, with plain water, after meals.

4. Rasraj Ras

This is a classical herbal formulation manufactured by Planet Ayurveda consisting of Parada (Purified mercury), Abhraka (Purified silica), and Swarna (calyx of gold), etc. Rasraj is widely famous for genetic conditions and can cross the blood-brain barrier that helps to control the various functions of the brain and may enhance its functioning ability. It supports the neuro-muscular system by pacifying the vata dosha effectively.

Dosage: 1 tablet twice daily to be chewed with plain water after meals.

5. Giloy Capsules

This is a patent herbal formulation prepared by Planet Ayurveda consisting of Giloy (Tinospora cordifolia) which is very effective in cleansing the blood streams and effective the management of various symptoms like slow down the degenerative processes and demyelinating conditions that hampers the normal walking and behavioural changes in the body. Giloy herb is famous for its tridosha balancing properties.

Dosage: 1 Capsule twice daily, with plain water, after meals.

6. Spirulina Capsules

This is a patent herbal formulation manufactured by Planet Ayurveda with a single herb Spirulina (Spirulina platensis). This is a form of algae, which is very useful in enhancing the immune system and achieving health goals for the person. It also acts as a nutritional supplement that helps to regain the strength of the body and make a difference in gait, balancing the vata dosha effectively. It alleviates weakness, fatigue, and muscular pain, maintaining a good bloodstream.

Dosage: 1 Capsule twice daily, with plain water, after meals.

Complication

Adrenoleukodystrophy, is a genetic disorder connected to X-linked chromosomes that affects the nervous system and adrenal glands. Ayurvedic management helps to eradicate these symptoms and nourish the whole body by maintaining immune health and other neuromuscular diseases. Its management mainly focuses on stopping or slowing down the progression of this adrenoleukodystrophy disease along with its complicated conditions that may occur with age. For more queries you can contact www.PlanetAyurveda.com

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Dr. Vikram Chauhan

Dr. Vikram Chauhan (MD - Ayurveda) is the CEO and Founder of Planet Ayurveda Pvt. Ltd. He is Author of the Book "Ayurveda – God’s Manual For Healing". He is an Ayurveda Expert Serving People worldwide through all the Possible Mediums, Operating from Main Branch in Mohali, India. With his Vast Experience in Herbs and their Applied Uses, he is successfully treating Numerous Patients suffering from Various Ailments with the help of Purest Herbal Supplements, Diet, and Lifestyle, according to the Principles of Ayurveda. For More Details, visit www.PlanetAyurveda.com.

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